Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 10/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753643 | 0.83 | MAPT (0.39) | NPC1CASP3RAB9ATNKS2MEN1 | |
| SCHEMBL18470279 | 0.80 | LIMK1 (0.50) | LIMK1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL754869 | 0.77 | MCL1 (0.33) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL17037076 | 0.75 | LIMK1 (0.49) | LIMK1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL753458 | 0.75 | GPR3 (0.39) | LIMK1RAB9ATNKS2MEN1KMT2A | |
| SCHEMBL18470294 | 0.73 | LIMK1 (0.41) | LIMK1ESR1TNKS2TNKS | |
| SCHEMBL17037062 | 0.73 | LIMK1 (0.41) | LIMK1ESR1TNKS2TNKS | |
| SCHEMBL26324938 | 0.73 | LIMK1 (0.41) | LIMK1ESR1TNKS2TNKS | |
| SCHEMBL23046392 | 0.72 | TNKS (0.46) | LIMK1NPC1RAB9ATNKS2MEN1 | |
| SCHEMBL12687983 | 0.72 | TNKS (0.46) | LIMK1NPC1RAB9ATNKS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138355-B2 | Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same | TOSOH CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20090261300-A1 | HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME | TOSOH CORPORATION (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090261300-A1 | HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME | AS3MT, TERT, TEAD1 | LIMK1 823/4885PIK3CG 2921/4885ESR1 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.