Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 19/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 19/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 19/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196594 | 0.76 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7526989 | 0.76 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7531538 | 0.69 | ADRA1D (0.46) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6787652 | 0.69 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6787658 | 0.69 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6787653 | 0.69 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7530647 | 0.69 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7944470 | 0.69 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6262192 | 0.68 | ADRA1D (0.50) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6199928 | 0.68 | ADRA1D (0.69) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010186-A1 | Dihydropyrimidines and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010186-A1 | Dihydropyrimidines and uses thereof | QDPR, DPYD, ADRA1D | ADRA1D 3/4885ADRA1A 4/4885ADRA1B 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.