Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glutathione Ethyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.65 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 9/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutathione Ethyl Ester SCHEMBL7527777 | 1.00 | PTGS1 (0.65) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione Ethyl Ester SCHEMBL7526098 | 0.98 | PTGS1 (0.65) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione Ethyl Ester SCHEMBL7530375 | 0.98 | PTGS1 (0.65) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione Ethyl Ester SCHEMBL7530345 | 0.96 | PTGS1 (0.71) | PTGS1GSTK1GLO1NOD1KMT2A | |
| Glutathione Ethyl Ester SCHEMBL9817298 | 0.96 | PTGS1 (0.71) | PTGS1GSTK1GLO1NOD1KMT2A | |
| Glutathione Ethyl Ester SCHEMBL680361 | 0.96 | PTGS1 (0.71) | PTGS1GSTK1GLO1NOD1KMT2A | |
| Glutathione Ethyl Ester SCHEMBL8749892 | 0.94 | PTGS1 (0.70) | PTGS1GSTK1GLO1NOD1KMT2A | |
| Glutathione Ethyl Ester SCHEMBL7529967 | 0.89 | PTGS1 (0.54) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione Ethyl Ester SCHEMBL7523000 | 0.89 | PTGS1 (0.54) | PTGS1GSTK1GLO1NOD1FNTA | |
| SCHEMBL19293518 | 0.88 | PTGS1 (0.59) | PTGS1GSTK1GLO1NOD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806432-B1 | Glutathione monoester sulfonate | KYOWA HAKKO KOGYO KK (JP) | 2002-03-20 | — | — | EP | disclosed |
| US-5756823-A | Glutathione monoester sulfonate | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0806432-A1 | Glutathione monoester sulfonate | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-11-12 | — | — | EP | disclosed |