Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360974 | 0.88 | ALDH1A1 (0.84) | POLBPKMALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6094287 | 0.84 | POLB (0.69) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL5347059 | 0.82 | ALDH1A1 (0.97) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL2061369 | 0.81 | PKM (0.76) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL1024915 | 0.81 | ALDH1A1 (0.73) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28137833 | 0.81 | ALDH1A1 (1.00) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL1027546 | 0.81 | ALDH1A1 (0.68) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL17007463 | 0.80 | ALDH1A1 (0.75) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL7647475 | 0.80 | ALDH1A1 (0.75) | POLBPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL13548648 | 0.80 | NPC1 (0.69) | POLBPKMALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |