Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765028 | 0.87 | HSP90AA1 (0.34) | HSP90AA1HCAR2MAPTLMNAMEN1 | |
| SCHEMBL6815090 | 0.83 | CNR2 (0.36) | HCAR2MAPTGRM2LMNARET | |
| SCHEMBL752898 | 0.79 | POLB (0.37) | MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL755282 | 0.75 | RIPK1 (0.33) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL752679 | 0.73 | CNR1 (0.34) | LMNAKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL2489939 | 0.73 | LIPG (0.49) | HSP90AA1 | |
| SCHEMBL752956 | 0.72 | LIPG (0.39) | HSP90AA1MEN1KMT2A | |
| SCHEMBL754893 | 0.72 | KMT2A (0.50) | HSP90AA1LMNAALDH1A1KMT2AMAPK1 | |
| SCHEMBL27861736 | 0.71 | MAPT (0.39) | HSP90AA1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL765412 | 0.70 | KMT2A (0.39) | HSP90AA1LMNAKMT2AMAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |