Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065523 | 0.93 | KDM4E (0.35) | HSD11B1KDM4EALDH1A1GAALMNA | |
| SCHEMBL8061265 | 0.92 | GAA (0.34) | HSD11B1KDM4EALDH1A1GAALMNA | |
| SCHEMBL8063589 | 0.91 | HSD11B1 (0.34) | HSD11B1KDM4EALDH1A1GAALMNA | |
| SCHEMBL8061132 | 0.89 | KDM4E (0.32) | HSD11B1KDM4EALDH1A1GAAHSD17B13 | |
| SCHEMBL8065625 | 0.89 | ANO1 (0.33) | HSD11B1KDM4EALDH1A1GAALMNA | |
| SCHEMBL8063668 | 0.88 | GAA (0.38) | KDM4EALDH1A1GAALMNAHSD17B13 | |
| SCHEMBL8061077 | 0.88 | S1PR3 (0.33) | HSD11B1KDM4EALDH1A1GAAADRB2 | |
| SCHEMBL8060058 | 0.88 | HTT (0.35) | HSD11B1KDM4EALDH1A1GAAANO1 | |
| SCHEMBL8061131 | 0.88 | ANO1 (0.33) | HSD11B1KDM4EALDH1A1GAALMNA | |
| SCHEMBL8048446 | 0.88 | ALDH1A1 (0.42) | ALDH1A1GAALMNACYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816328-B1 | Process for the manufacture of acetonylbenzamides | DOW AGROSCIENCES LLC (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-0816331-B1 | Fungicidally active n-acetonylbenzamide compounds | ROHM & HAAS (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5969200-A | CHLORINATING PARA-TOLUOYL CHLORIDE IN PRESENCE OF CHLORINE GAS AND ALUMINUM CHLORIDE OR ANTIMONY CHLORIDE CATALYST, DISTILLING MIXTURE PRODUCED TO RECOVER 3,5-DICHLORO-4-METHYLBENZOYL CHLORIDE | ROHM AND HAAS COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5945565-A | SYNTHESIS OF 4-AMINO-3-CHLORO-5-(METHOXYIMINOMETHYL)BENZOYL CHLORIDE STARTING WITH THE CONVERSION OF 5-METHYL-4-NITRO-BENZOIC ACID TO 4-NITRO-5-(METHOXYIMINOMETHYL)-BENZOIC ACID, METHYL ESTER | ROHM AND HAAS COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5929098-A | Fungicidically active N-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5874466-A | REACTING AMINE AND ACYL CHLORIDE, HYDROGENOLYSIS | ROHM AND HAAS COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0816331-A1 | Fungicidally active n-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0816328-A2 | Process for the manufacture of acetonylbenzamides | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |