Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586167 | 0.88 | MAPT (0.61) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL2049320 | 0.88 | MAPT (0.61) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL29557291 | 0.88 | MAPT (0.61) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL195997 | 0.88 | MAPT (0.61) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL29527665 | 0.88 | MAPT (0.61) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL29499673 | 0.88 | MAPT (0.61) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL5925150 | 0.85 | MAPT (0.54) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL27312034 | 0.85 | MAPT (0.54) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL7811480 | 0.85 | MAPT (0.54) | SCN9AMAPTALDH1A1KDM4ECASP1 | |
| SCHEMBL3855559 | 0.83 | ALDH1A1 (0.52) | SCN9AMAPTALDH1A1KDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842193-B1 | SOMATOSTATIN-ANALOGOUS CYCLIC PEPTIDES WITH INHIBITORY ACTIVITY ON GROWTH HORMONE | DEGHENGHI ROMANO (CH) | 2002-02-27 | — | — | EP | disclosed |
| EP-0842193-A1 | SOMATOSTATIN-ANALOGOUS CYCLIC PEPTIDES WITH INHIBITORY ACTIVITY ON GROWTH HORMONE | DEGHENGHI, Romano (CH) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005167-A1 | SOMATOSTATIN-ANALOGOUS CYCLIC PEPTIDES WITH INHIBITORY ACTIVITY ON GROWTH HORMONE | DEGHENGHI ROMANO (CH) | 1997-02-13 | — | — | WO | disclosed |