Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.42 |
| ▸ | CA1 | P00915 | 16/20 | 0.42 |
| ▸ | MMP2 | P08253 | 7/20 | 0.42 |
| ▸ | MMP9 | P14780 | 7/20 | 0.42 |
| ▸ | MMP1 | P03956 | 6/20 | 0.42 |
| ▸ | MMP8 | P22894 | 6/20 | 0.42 |
| ▸ | MMP13 | P45452 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180239 | 0.81 | CA1 (0.37) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL810240 | 0.81 | CA1 (0.37) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL5180906 | 0.81 | CA1 (0.37) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL5180231 | 0.81 | CA1 (0.37) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL5180894 | 0.81 | CA1 (0.37) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL19042219 | 0.81 | CA2 (0.46) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL2526371 | 0.78 | HCRTR2 (0.34) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL19042350 | 0.78 | CA1 (0.48) | CA2CA1MMP2MMP9MMP1 | |
| SCHEMBL11338159 | 0.76 | CA1 (0.47) | CA2CA1MMP2MMP9MMP1 | |
| Benzene SCHEMBL5180623 | 0.75 | MMP2 (0.33) | CA2CA1MMP2MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | claimed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | claimed |
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | disclosed |