Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527645 | 1.00 | LMNA (0.42) | LMNACETPPKMTRPV1TRPA1 | |
| SCHEMBL7531868 | 0.95 | LMNA (0.42) | LMNACETPPKMMEN1CYP3A4 | |
| SCHEMBL7531864 | 0.95 | LMNA (0.42) | LMNACETPPKMMEN1CYP3A4 | |
| SCHEMBL7522606 | 0.84 | CETP (0.43) | LMNACETPPKMKMT2A | |
| SCHEMBL7532833 | 0.84 | CETP (0.43) | LMNACETPPKMKMT2A | |
| SCHEMBL7522855 | 0.84 | CETP (0.43) | LMNACETPPKMKMT2A | |
| SCHEMBL23489753 | 0.80 | GPR84 (0.41) | LMNACETPPKMCYP3A4BLM | |
| SCHEMBL5804470 | 0.80 | GPR84 (0.41) | LMNACETPPKMCYP3A4BLM | |
| SCHEMBL8535016 | 0.80 | GPR84 (0.41) | LMNACETPPKMCYP3A4BLM | |
| SCHEMBL9177080 | 0.78 | GPR84 (0.45) | LMNACETPCYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842915-B1 | Optically active alcohol and process for the production thereof | MITSUBISHI GAS CHEMICAL CO (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0842915-A2 | Optically active alcohol and process for the production thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-05-20 | — | — | EP | disclosed |