1-Naphthol

1-Naphthol

SCHEMBL7527709

O=S(=O)(O)NS(=O)(=O)O.Oc1cccc2ccccc12

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.65
CA2 P00918 2/20 0.46
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
HCRTR1 O43613 1/20 0.45
CDK2 P24941 1/20 0.44
ERN1 O75460 1/20 0.43
G6PD P11413 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
KEAP1 Q14145 1/20 0.42
PTPN22 Q9Y2R2 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALOX12 P18054 1/20 0.41
PLAU P00749 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
LDHA P00338 1/20 0.40
MAPKAPK2 P49137 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL29216682 0.88 CYP1A2 (0.71) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL7714764 0.88 CYP1A2 (0.77) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL30669386 0.88 CYP1A2 (0.77) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL10605017 0.86 CYP1A2 (0.74) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL27594854 0.86 CYP1A2 (0.74) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL10605020 0.86 CYP1A2 (0.74) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL28395998 0.86 CYP1A2 (0.74) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL28825167 0.84 CYP1A2 (0.71) CYP1A2CA2CA1CA9HCRTR1
1-Naphthol SCHEMBL28254099 0.83 CYP1A2 (0.94) CYP1A2CA2HSD17B1HSD17B2KEAP1
1-Naphthol SCHEMBL27455138 0.82 KEAP1 (0.57) CYP1A2CA2CA1CA9HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002010251-A1 METHOD FOR MAKING POLYPYRROLE POLYMERITS CO., LTD. (KR) 2002-02-07 WO claimed
WO-2002010251-A1 METHOD FOR MAKING POLYPYRROLE POLYMERITS CO., LTD. (KR) 2002-02-07 WO disclosed
CN-1235992-A Water-soluble fiber-reactive dyes, processes for their preparation and their use HOECHST AG (DE) 1999-11-24 CN disclosed
CN-1112588-A Black fiber-reactive azo dye mixtures and use thereof for dyeing hydroxy- and/or caroboxamido-containing fiber material HOECHST AG (DE) 1995-11-29 CN disclosed
CN-1108277-A Water-soluble fibre-reactive dyes, their preparation and their use HOECHST AG (DE) 1995-09-13 CN disclosed