Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004505 | 0.81 | PLA2G7 (0.38) | PLA2G7MAPT | |
| SCHEMBL7007975 | 0.80 | KMT2A (0.40) | PLA2G7MAPT | |
| SCHEMBL7011218 | 0.79 | PLA2G7 (0.44) | PLA2G7 | |
| SCHEMBL7012920 | 0.79 | PLA2G7 (0.44) | PLA2G7 | |
| SCHEMBL7529761 | 0.76 | PLA2G7 (0.41) | PLA2G7MAPT | |
| SCHEMBL7530971 | 0.76 | ALDH1A1 (0.43) | MAPT | |
| SCHEMBL7011062 | 0.72 | PLA2G7 (0.46) | PLA2G7 | |
| SCHEMBL7011203 | 0.71 | PLA2G7 (0.41) | PLA2G7 | |
| SCHEMBL7010646 | 0.70 | PLA2G7 (0.39) | PLA2G7 | |
| SCHEMBL7013475 | 0.70 | PLA2G7 (0.39) | PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175409-A1 | PYRIMIDINONES DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000068208-A1 | PYRIMIDINONES DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-16 | — | — | WO | disclosed |