Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240230 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL330429 | 0.76 | — | — | |
| SCHEMBL11880727 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL9154269 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL1534917 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL9512614 | 0.76 | LMNA (0.36) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL9152747 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL330197 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL11691906 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL29595562 | 0.76 | SIGMAR1 (0.42) | HLCSLMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131226-C | Novel 1,2-amylic cycle disulfide, its preparation process and medicinal compoisitions containing same | ADIR (FR) | 2003-12-17 | — | — | CN | disclosed |
| EP-1010698-B1 | 1,2-dithiolane derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-27 | — | — | EP | disclosed |
| US-6150358-A | USEFUL IN THE TREATMENT OF DISEASE FOR WHICH THE USE OF ANTI-OXIDATION AGENT IS REQUIERED SUCH AS NEURODEGENRATIVE DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-21 | — | — | US | disclosed |
| EP-1010698-A1 | 1,2-dithiolane derivatives, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |
| CN-1257072-A | Novel 1,2-amylic cycle disulfide, its preparation process and medicinal compoisitions containing same | ADIR (FR) | 2000-06-21 | — | — | CN | disclosed |