SCHEMBL7528074

SCHEMBL7528074

CCC(=O)OC(C([O])=O)C(O)CO

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527477 0.85 MAPT (0.41) MEN1KMT2AMAPTMAPK1
SCHEMBL7532569 0.79 TSHR (0.37) MAPT
SCHEMBL4616283 0.78 MEN1 (0.33) MEN1CYP2C19RECQLKMT2AMAPT
SCHEMBL18877228 0.77 MEN1 (0.35) MEN1CYP2C19RECQLKMT2AMAPT
SCHEMBL5847222 0.75 MEN1 (0.34) MEN1CYP2C19RECQLKMT2AMAPT
SCHEMBL16144866 0.74 LMNA (0.38)
SCHEMBL10500851 0.73 MEN1 (0.33) MEN1CYP2C19RECQLKMT2AMAPT
SCHEMBL12475543 0.73 MEN1 (0.33) MEN1CYP2C19RECQLKMT2AMAPT
SCHEMBL9698326 0.73 MEN1 (0.33) MEN1CYP2C19RECQLKMT2AMAPT
SCHEMBL9638912 0.73 MAPT (0.36) MEN1CYP2C19RECQLKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1192140-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS Bayer Aktiengesellschaft (DE) 2002-04-03 EP claimed
WO-2000078734-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 2000-12-28 WO claimed
EP-1192140-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS Bayer Aktiengesellschaft (DE) 2002-04-03 EP disclosed
WO-2000078734-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 2000-12-28 WO disclosed