Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847228 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AUSP2MAPTMAPK1 | |
| SCHEMBL9698326 | 0.81 | MEN1 (0.33) | MEN1KMT2ACYP2C19RECQLMAPT | |
| SCHEMBL18877228 | 0.80 | MEN1 (0.35) | MEN1KMT2ACYP2C19RECQLUSP2 | |
| SCHEMBL4616283 | 0.77 | MEN1 (0.33) | MEN1KMT2ACYP2C19RECQLMAPT | |
| SCHEMBL10500851 | 0.77 | MEN1 (0.33) | MEN1KMT2ACYP2C19RECQLMAPT | |
| SCHEMBL12475543 | 0.77 | MEN1 (0.33) | MEN1KMT2ACYP2C19RECQLMAPT | |
| SCHEMBL9638912 | 0.77 | MAPT (0.36) | MEN1KMT2ACYP2C19RECQLMAPT | |
| SCHEMBL4624024 | 0.76 | MEN1 (0.31) | MEN1KMT2ACYP2C19RECQLMAPT | |
| SCHEMBL18877226 | 0.75 | LMNA (0.39) | MEN1KMT2ACYP2C19RECQLUSP2 | |
| SCHEMBL7528074 | 0.75 | MEN1 (0.33) | MEN1KMT2ACYP2C19RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | claimed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | claimed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | claimed |
| EP-0759908-A1 | SUBSTITUTED DIAZACYCLOHEXANDI(THI)ONES | BAYER AG (DE) | 1997-03-05 | — | — | EP | claimed |
| WO-1995031440-A1 | SUBSTITUTED DIAZACYCLOHEXANDI(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-23 | — | — | WO | claimed |
| EP-0251294-B1 | SUBSTITUTED ISOQUINOLINE DERIVATIVES AND ANTI-ULCER AGENTS | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-09-19 | — | — | EP | claimed |
| EP-0112191-B1 | 4-(1H-INDOLYL-3-)-ALPHA-METHYL PIPERIDINE-1-ETHANOL DERIVATIVES, THEIR SALTS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS MEDICINES | ROUSSEL-UCLAF (FR) | 1987-02-04 | — | — | EP | claimed |
| US-6992044-B1 | Substituted phenyluracils | BAYER CROPSCIENCE AG (DE) | 2006-01-31 | — | — | US | disclosed |
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
| US-6429203-B1 | PHOSPHOSESQUITERPENES USED TO TREAT CANCER; REDUCED SIDE EFFECTS | INTERNATIONAL PHYTOCHEMISTRY RESEARCH LABS, LTD. | 2002-08-06 | — | — | US | disclosed |
| US-6268394-B1 | CONTACTING A CELL WITH AN AMOUNT OF A SESQUITERPENE LACTONE | INTERNATIONAL PHYTOCHEMISTRY RESEARCH LABS, LTD. | 2001-07-31 | — | — | US | disclosed |
| EP-1056450-A1 | FARNESYL-PROTEIN TRANSFERASE INHIBITORS | International Phytochemistry Research Labs, Ltd. (US) | 2000-12-06 | — | — | EP | disclosed |
| US-6150375-A | INHIBITORS OF BOTH OF THE HUMAN 5AR ISOZYMES; BENIGN PROSTATE HYPERPLASIA, MALE PATTERN BALDNESS, ACNE VULGARIS, SEBORRHEA, ANDROGENIC ALOPECIA, HIRSUTISM AND PROSTATE CANCER; BLOCKS THE CONVERSION OF TESTOSTERONE TO 5-ALPHA-DIHYDROTESTOSTERONE | ELI LILLY AND COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| US-6051565-A | Farnesyl-protein transferase inhibitors | INTERNATIONAL PHYTOCHEMISTRY RESEARCH LABS, LTD. (US) | 2000-04-18 | — | — | US | disclosed |
| WO-1999043314-A1 | FARNESYL-PROTEIN TRANSFERASE INHIBITORS | INTERNATIONAL PHYTOCHEMISTRY RESEARCH LABS, LTD. (US) | 1999-09-02 | — | — | WO | disclosed |
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0251998-A2 | Phenylsulfonylureas | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | MEN1 3334/4885KMT2A 1862/4885CYP2C19 429/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | MEN1 3334/4885KMT2A 1862/4885CYP2C19 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.