SCHEMBL7528294

SCHEMBL7528294

CCc1ccc(N)cc1CCS

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.39
ACHE P22303 1/20 0.38
GAA P10253 4/20 0.37
MAPT P10636 3/20 0.37
MAPK1 P28482 2/20 0.37
HTT P42858 2/20 0.37
TSHR P16473 1/20 0.37
DHFR P00374 1/20 0.35
BACE1 P56817 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 3/20 0.33
GFER P55789 1/20 0.33
HSP90AA1 P07900 1/20 0.33
FOLH1 Q04609 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CASP1 P29466 2/20 0.31
KMT2A Q03164 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15835001 0.83 PRKCI (0.41) PRKCIACHEGAAMAPTMAPK1
SCHEMBL29738343 0.83 PRKCI (0.47) PRKCIACHEGAAMAPTMAPK1
SCHEMBL395438 0.83 PRKCI (0.47) PRKCIACHEGAAMAPTMAPK1
SCHEMBL18430312 0.80 PRKCI (0.39) PRKCIACHEGAAMAPTMAPK1
SCHEMBL22271585 0.80 TYR (0.44) PRKCIACHEGAAMAPTMAPK1
SCHEMBL5374018 0.79 PRKCI (0.44) PRKCIACHEGAAMAPTMAPK1
Formaldehyde SCHEMBL28270525 0.79 PRKCI (0.44) PRKCIACHEGAAMAPTMAPK1
SCHEMBL28767876 0.77 GAA (0.43) PRKCIACHEGAAMAPTMAPK1
SCHEMBL5831415 0.77 GPR84 (0.47) GAAMAPTHTTTSHRALDH1A1
SCHEMBL27694979 0.77 CASP1 (0.39) PRKCIGAAMAPTMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180355189-A1 ANTI-BIOFOULING COATING BASED ON EPOXY RESIN AND AMINE-FUNCTIONAL POLYSILOXANE ROHM AND HAAS COMPANY 2018-12-13 US disclosed
EP-3397706-A1 ANTI-BIOFOULING COATING BASED ON EPOXY RESIN AND AMINE-FUNCTIONAL POLYSILOXANE Dow Global Technologies LLC (US) 2018-11-07 EP disclosed
WO-2017113149-A1 ANTI-BIOFOULING COATING BASED ON EPOXY RESIN AND AMINE-FUNCTIONAL POLYSILOXANE DOW GLOBAL TECHNOLOGIES LLC (US) 2017-07-06 WO disclosed
EP-0669949-B1 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS COGNIS CORP (US) 2002-03-13 EP disclosed
EP-0669949-A4 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS. HENKEL CORP (US) 1996-07-10 EP disclosed
EP-0669949-A1 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS HENKEL CORPORATION (US) 1995-09-06 EP disclosed
US-5444127-A Urea, thiourea, guanidine derivatives, curing agents for epoxy resins, odorless, low temperature HENKEL CORPORATION (US) 1995-08-22 US disclosed
WO-1994009051-A1 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS HENKEL CORPORATION (US) 1994-04-28 WO disclosed
EP-0014745-B1 CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE DIAMOND SHAMROCK CORPORATION (US) 1983-05-25 EP disclosed
EP-0075827-A2 Polyepoxide curing by polymercaptans plus catalytic co-curing agents DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-04-06 EP disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed