Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | NPY4R | P50391 | 8/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.51 |
| ▸ | NPY1R | P25929 | 6/20 | 0.51 |
| ▸ | NPY2R | P49146 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530557 | 1.00 | KISS1R (0.52) | KISS1RHPGDSCTSVCTSLCTSB | |
| SCHEMBL7525098 | 0.90 | KISS1R (0.54) | KISS1RHPGDSCTSLNPY4RNPY5R | |
| SCHEMBL7535309 | 0.90 | KISS1R (0.54) | KISS1RHPGDSCTSLNPY4RNPY5R | |
| SCHEMBL7531488 | 0.89 | KISS1R (0.52) | KISS1RHPGDSCTSBNPY4RNPY5R | |
| SCHEMBL24179840 | 0.84 | KISS1R (0.56) | KISS1RCTSLCTSSCTSKNPY4R | |
| SCHEMBL7529600 | 0.84 | KISS1R (0.56) | KISS1RHPGDSNPY4RNPY5RNPY1R | |
| SCHEMBL7523407 | 0.84 | NPY4R (0.51) | KISS1RCTSBNPY4RNPY5RNPY1R | |
| SCHEMBL7535795 | 0.82 | NPY4R (0.59) | CTSLNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30064048 | 0.82 | NPY4R (0.59) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL7532875 | 0.81 | KISS1R (0.54) | KISS1RNPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |