Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.59 |
| ▸ | NPY1R | P25929 | 8/20 | 0.59 |
| ▸ | NPY2R | P49146 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.52 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.52 |
| ▸ | CHRNG | P07510 | 1/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.52 |
| ▸ | CHRND | Q07001 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064048 | 0.91 | NPY4R (0.59) | NPY4RNPY5RNPY1RNPY2RQRFPR | |
| SCHEMBL9058352 | 0.89 | NPY4R (0.57) | NPY4RNPY5RNPY1RNPY2RQRFPR | |
| SCHEMBL30045851 | 0.88 | KISS1R (0.61) | NPY4RNPY5RNPY1RNPY2RPTPN1 | |
| SCHEMBL13563450 | 0.88 | NPY4R (0.64) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL3356931 | 0.88 | NPY4R (0.64) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL3356923 | 0.88 | NPY4R (0.64) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29624352 | 0.87 | NPY4R (0.57) | NPY4RNPY5RNPY1RNPY2RCTSL | |
| SCHEMBL13563435 | 0.87 | KISS1R (0.62) | NPY4RNPY5RNPY1RNPY2RPTPN1 | |
| SCHEMBL12792618 | 0.87 | KISS1R (0.62) | NPY4RNPY5RNPY1RNPY2RPTPN1 | |
| SCHEMBL16181287 | 0.85 | NPY1R (0.55) | NPY4RNPY5RNPY1RNPY2RCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |