Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81300 | 0.87 | ACP3 (0.52) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| SCHEMBL31742347 | 0.87 | ACP3 (0.52) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| Hydrochloric Acid SCHEMBL28699780 | 0.85 | ACP3 (0.50) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| Formaldehyde SCHEMBL3281282 | 0.83 | PTK2B (0.52) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| Water SCHEMBL28995210 | 0.83 | ACP3 (0.48) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| SCHEMBL31742341 | 0.77 | HPRT1 (0.54) | ACP3PTK2BL3MBTL1CA12CA14 | |
| SCHEMBL2576858 | 0.77 | HPRT1 (0.54) | ACP3PTK2BL3MBTL1CA12CA14 | |
| SCHEMBL457045 | 0.76 | ACP3 (0.48) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| SCHEMBL339616 | 0.75 | ACP3 (0.52) | ACP3PLK1PTK2BL3MBTL1MMP3 | |
| SCHEMBL4388890 | 0.74 | PTK2B (0.42) | ACP3PTK2BL3MBTL1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476372-B2 | Polyester fiber and method for its production, and tire cord, tire, belt-reinforcing fiber material and belt comprising the polyester fiber | TEIJIN FIBERS LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| EP-2261403-B1 | POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER | TEIJIN FIBERS LTD (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20110017378-A1 | POLYESTER FIBER AND METHOD FOR ITS PRODUCTION, AND TIRE CORD, TIRE, BELT-REINFORCING FIBER MATERIAL AND BELT COMPRISING THE POLYESTER FIBER | TEIJIN FIBERS LIMITED (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2261403-A1 | POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER | Teijin Fibers Limited (JP) | 2010-12-15 | — | — | EP | disclosed |