SCHEMBL7528593

SCHEMBL7528593

CCC(OC(=O)/C(C)=C/O)Oc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 10/20 0.42
ELANE P08246 1/20 0.41
MAPT P10636 2/20 0.38
MAPK1 P28482 2/20 0.38
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
DRD2 P14416 1/20 0.37
DRD1 P21728 1/20 0.37
DRD3 P35462 1/20 0.37
RAB9A P51151 1/20 0.36
AKR1C3 P42330 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR1 P03372 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
HMGB1 P09429 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1415830 1.00 ABCB1 (0.42) ABCB1ELANEMAPTMAPK1LTB4R
SCHEMBL7522851 0.84 ALDH1A1 (0.39) ABCB1MAPTRAB9AAKR1C3KDM4E
SCHEMBL1415649 0.84 ALDH1A1 (0.39) ABCB1MAPTRAB9AAKR1C3KDM4E
SCHEMBL28135705 0.81 ABCB1 (0.46) ABCB1ELANEMAPTDRD2DRD1
SCHEMBL7526201 0.78 ALDH1A1 (0.39) ABCB1AKR1C3KDM4EALDH1A1HPGD
SCHEMBL3787914 0.77 ABCB1 (0.46) ABCB1ELANEMAPTMAPK1DRD2
SCHEMBL7526211 0.77 ALDH1A1 (0.42) ABCB1MAPTAKR1C3ALDH1A1HPGD
SCHEMBL8441759 0.76 ABCB1 (0.44) ABCB1ELANEMAPTMAPK1DRD2
SCHEMBL28192280 0.74 ELANE (0.51) ABCB1ELANEMAPTMAPK1DRD2
SCHEMBL16026389 0.73 PPARA (0.32) LTB4RLTB4R2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020146515-A1 Aqueous compositions for coating metal components BASF AKTIENGESELLSCHAFT (DE) 2002-10-10 US disclosed
US-6242515-B1 ESPECIALLY SEALING POLYURETHANE FOAMS WITH A CURABLE MIXTURE OF AN ADDITION COPOLYMER CONTAINING CARBONYL GROUPS AND A DI-OR POLYCARBOXYLIC ACID HYDRAZIDE BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed
US-5763012-A PROTECTIVE COATINGS AND SEALS BASF AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed