SCHEMBL7526211

SCHEMBL7526211

CCC(COC(=O)c1ccccc1C(=O)c1ccccc1)OC(=O)C(C)=CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CYP1A2 P05177 1/20 0.42
TSHR P16473 2/20 0.42
CA2 P00918 1/20 0.41
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 2/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
AKR1C3 P42330 1/20 0.36
ABCB1 P08183 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522851 0.82 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP3A4CYP2C9CYP2C19
SCHEMBL9503922 0.81 ALDH1A1 (0.44) ALDH1A1L3MBTL1CYP3A4CYP2C9CYP2C19
SCHEMBL7526201 0.78 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP3A4CYP2C9CYP2C19
SCHEMBL1415646 0.77 L3MBTL1 (0.49) ALDH1A1L3MBTL1CYP3A4CYP2C9CYP2C19
SCHEMBL1415830 0.77 ABCB1 (0.42) ALDH1A1TSHRMAPTHPGDAKR1C3
SCHEMBL7528593 0.77 ABCB1 (0.42) ALDH1A1TSHRMAPTHPGDAKR1C3
SCHEMBL6929436 0.76 TSHR (0.51) ALDH1A1L3MBTL1CYP3A4TSHRCA2
SCHEMBL194749 0.75 ALDH1A1 (0.47) ALDH1A1L3MBTL1CYP3A4TSHRCA2
SCHEMBL8164653 0.74 KMT2A (0.33) ALDH1A1TSHRPRSS1KMT2AMEN1
SCHEMBL16046114 0.72 ALDH1A1 (0.53) ALDH1A1L3MBTL1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020146515-A1 Aqueous compositions for coating metal components BASF AKTIENGESELLSCHAFT (DE) 2002-10-10 US disclosed
US-6242515-B1 ESPECIALLY SEALING POLYURETHANE FOAMS WITH A CURABLE MIXTURE OF AN ADDITION COPOLYMER CONTAINING CARBONYL GROUPS AND A DI-OR POLYCARBOXYLIC ACID HYDRAZIDE BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed
US-5763012-A PROTECTIVE COATINGS AND SEALS BASF AKTIENGESELLSCHAFT (DE) 1998-06-09 US disclosed