Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30197097 | 0.85 | GFER (0.46) | TAAR1MAPTTP53MEN1KMT2A | |
| SCHEMBL1029106 | 0.85 | GFER (0.46) | TAAR1MAPTTP53MEN1KMT2A | |
| SCHEMBL14468524 | 0.78 | HDAC4 (0.42) | TAAR1MAPTGAAALDH1A1KDM4E | |
| SCHEMBL11775418 | 0.76 | ALDH1A1 (0.46) | TAAR1MAPTTP53MEN1KMT2A | |
| SCHEMBL9365623 | 0.75 | ALDH1A1 (0.52) | MAPTTP53MEN1KMT2AGFER | |
| Hydrochloric Acid SCHEMBL9437914 | 0.74 | ALDH1A1 (0.50) | MAPTTP53MEN1KMT2AGFER | |
| SCHEMBL2215316 | 0.73 | TSHR (0.55) | TAAR1MAPTMEN1KMT2AGFER | |
| SCHEMBL13996971 | 0.73 | NPSR1 (0.45) | MAPTTP53MEN1KMT2AGFER | |
| SCHEMBL11146469 | 0.72 | ALDH1A1 (0.50) | MAPTTP53MEN1KMT2AGFER | |
| SCHEMBL681549 | 0.72 | ALDH1A1 (0.48) | MAPTTP53MEN1KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |