Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30197097 | 1.00 | GFER (0.46) | GFERALDH1A1CYP3A4TAAR1LMNA | |
| SCHEMBL11775418 | 0.90 | ALDH1A1 (0.46) | GFERALDH1A1CYP3A4TAAR1LMNA | |
| SCHEMBL9365623 | 0.89 | ALDH1A1 (0.52) | GFERALDH1A1CYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL9437914 | 0.87 | ALDH1A1 (0.50) | GFERALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL9644057 | 0.85 | ALDH1A1 (0.48) | GFERALDH1A1CYP3A4TAAR1LMNA | |
| SCHEMBL681549 | 0.85 | ALDH1A1 (0.48) | GFERALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL11146469 | 0.85 | ALDH1A1 (0.50) | GFERALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL7528609 | 0.85 | TAAR1 (0.49) | GFERALDH1A1TAAR1LMNATSHR | |
| SCHEMBL457496 | 0.85 | ALDH1A1 (0.61) | GFERALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL30565134 | 0.85 | ALDH1A1 (0.61) | GFERALDH1A1CYP3A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115637057-B | Synthesis method of double-crosslinking azo disperse dye | 绍兴文理学院 | 2023-10-20 | — | — | CN | claimed |
| CN-115637057-A | Synthesis method of double-crosslinking azo disperse dye | 绍兴文理学院 | 2023-01-24 | — | — | CN | claimed |
| CN-112679366-A | Purification method of N- (2-aminoethyl) -N-ethyl m-toluidine | 上海俪源科技有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-112552187-A | Purification method of N- (2-aminoethyl) -N-ethyl m-toluidine | 上海俪源科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| US-8557796-B2 | Substituted 1-oxa-2,8-diaza-spiro [4,5] dec-2-ene derivatives and related treatment methods | GRUENENTHAL GMBH (DE) | 2013-10-15 | — | — | US | claimed |
| US-7968591-B2 | 1,3-disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their use in medicaments | GRUENENTHAL GMBH (DE) | 2011-06-28 | — | — | US | claimed |
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| US-20090137573-A1 | 1,3-Disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their Use in Medicaments | GRUENENTHAL GMBH (DE) | 2009-05-28 | — | — | US | claimed |
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | claimed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-115637057-B | Synthesis method of double-crosslinking azo disperse dye | 绍兴文理学院 | 2023-10-20 | — | — | CN | disclosed |
| EP-3152210-B1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-115637057-A | Synthesis method of double-crosslinking azo disperse dye | 绍兴文理学院 | 2023-01-24 | — | — | CN | disclosed |
| US-4260679-A | Method and reagent for the quantitative determination of hydrogen peroxide and precursors thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1981-04-07 | — | — | US | disclosed |
| EP-0007787-A1 | Method and reagent for the quantitative determination of hydrogen peroxide | KYOWA HAKKO KOGYO CO., LTD (JP) | 1980-02-06 | — | — | EP | disclosed |
| US-4098783-A | Dye substituted cyclic 1,3-sulfur-nitrogen compounds as dye image-forming materials in photography | POLAROID CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4038240-A | PROCESS FOR DYEING POLYURETHANE RESINS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137573-A1 | 1,3-Disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their Use in Medicaments | OPRL1, TPH1, OPRK1 | GFER 3535/4885ALDH1A1 2168/4885CYP3A4 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.