Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526974 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7519971 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7522473 | 0.79 | MTNR1A (0.64) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7521096 | 0.79 | MTNR1A (0.98) | MTNR1AMTNR1B | |
| SCHEMBL7517761 | 0.78 | MTNR1A (1.00) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7520703 | 0.77 | MTNR1A (0.93) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7520556 | 0.76 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL7526198 | 0.76 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL7563666 | 0.75 | MTNR1A (0.78) | MTNR1AMTNR1B | |
| SCHEMBL7521018 | 0.72 | MTNR1A (0.56) | MTNR1AMTNR1BCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |