SCHEMBL7528812

SCHEMBL7528812

O=C1C(O)=C(O)C(=O)C(Cl)=C1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.57
ALDH1A1 P00352 4/20 0.57
MAPT P10636 4/20 0.57
TDP1 Q9NUW8 3/20 0.57
MEN1 O00255 3/20 0.57
ALOX15 P16050 3/20 0.57
ALOX12 P18054 3/20 0.57
KMT2A Q03164 3/20 0.57
HSD17B10 Q99714 3/20 0.57
MAPK1 P28482 3/20 0.57
CES2 O00748 2/20 0.57
BCHE P06276 2/20 0.57
ACHE P22303 2/20 0.57
CES1 P23141 2/20 0.57
BLM P54132 2/20 0.57
TP53 P04637 2/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 2/20 0.57
TSHR P16473 1/20 0.57
RECQL P46063 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052798 0.86 KDM4E (0.60) KDM4EALDH1A1MAPTTDP1MEN1
SCHEMBL223460 0.85 ALDH1A1 (0.47) KDM4EALDH1A1MAPTTDP1MEN1
SCHEMBL27797012 0.81 KDM4E (0.44) KDM4EALDH1A1MAPTTDP1MEN1
SCHEMBL929847 0.81 KDM4E (0.44) KDM4EALDH1A1MAPTTDP1MEN1
SCHEMBL5081810 0.81 KDM4E (0.44) KDM4EALDH1A1MAPTTDP1MEN1
Water SCHEMBL9062657 0.81 KDM4E (0.50) KDM4EALDH1A1MAPTTDP1MEN1
SCHEMBL3320693 0.81 KDM4E (0.44) KDM4EALDH1A1MAPTTDP1MEN1
SCHEMBL5081850 0.81 KDM4E (0.44) KDM4EALDH1A1MAPTTDP1MEN1
Chloranil SCHEMBL28898402 0.79 KDM4E (0.90) KDM4EALDH1A1MAPTTDP1MEN1
Tetroquinone SCHEMBL167587 0.74 KDM4E (1.00) KDM4EALDH1A1MAPTTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1104441-C Modified polyalkadiene-containing compositions LORD CORP (US) 2003-04-02 CN disclosed
EP-0866809-B1 MODIFIED POLYALKADIENE-CONTAINING COMPOSITIONS LORD CORP (US) 2002-03-20 EP disclosed
CN-1202908-A Modified polyalkadiene-containing compositions LORD CORP (US) 1998-12-23 CN disclosed
US-5686426-A Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1997-11-11 US disclosed
US-5663151-A ANTIINFLAMMATORY AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1997-09-02 US disclosed
US-5565433-A ADMINISTERING IN TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-15 US disclosed
EP-0719787-A1 Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1996-07-03 EP disclosed
CN-1112122-A Sulfated-glycolipid derivatives as cell adhesion inhibitors BRISTOL MYERS SQUIBB CO (US) 1995-11-22 CN disclosed
CN-1111638-A Sulfated-glycolipid derivatives as cell adhesion inhibitors BRISTOL MYERS SQUIBB CO (US) 1995-11-15 CN disclosed
EP-0671407-A2 Sulfated alpha-glycolipid derivatives as cell adhesion inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1995-09-13 EP disclosed
EP-0671406-A2 Sulfated beta-glycolipid derivatives as cell adhesion inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1995-09-13 EP disclosed
CN-1008632-B STRUCTURAL ADHESIVE FORMULATION LORD CORP (US) 1990-07-04 CN disclosed
US-4703089-A HEAT CURABLE ADDITION POLYMERS, POLYURETHANES; BRONSTED ACID CATALYSTS, REDUCIBLE METAL COMPONENTS, SULFONYL HALIDES; BLENDS FOR METAL BONDING LORD CORPORATION, A CORP. OF PA 1987-10-27 US disclosed