Phosphonic Acid

Phosphonic Acid

SCHEMBL7528825

Clc1nc(Cl)nc(Cl)n1.O=[PH](O)O

nearest known ligand 0.57

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
ALOX15 P16050 1/20 0.57
TSHR P16473 1/20 0.57
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL7523130 1.00 ALDH1A1 (0.57) ALDH1A1ALOX15TSHRLMNA
Phosphonic Acid SCHEMBL11518648 0.80 ALDH1A1 (0.35) ALDH1A1ALOX15TSHRLMNA
SCHEMBL1332087 0.76
SCHEMBL20781 0.76
Methyl Alcohol SCHEMBL27883764 0.72 ALDH1A1 (0.73) ALDH1A1ALOX15TSHRLMNA
Urea SCHEMBL697365 0.71 ALDH1A1 (0.57) ALDH1A1ALOX15TSHRLMNA
SCHEMBL31212831 0.71 ALDH1A1 (0.89) ALDH1A1ALOX15TSHRLMNA
SCHEMBL28850556 0.71 ALDH1A1 (0.89) ALDH1A1ALOX15TSHRLMNA
Hydrochloric Acid SCHEMBL11176077 0.71 ALDH1A1 (0.89) ALDH1A1ALOX15TSHRLMNA
SCHEMBL1163861 0.71 ALDH1A1 (0.89) ALDH1A1ALOX15TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617717-B1 PHOSPHORUS-CONTAINING TRIAZINE COMPOUNDS AND THEIR USE AKZO NOBEL UK LTD (GB) 2002-03-13 EP disclosed
US-5534573-A FLAME RETARDANTS COURTAULDS PLC (GB) 1996-07-09 US disclosed
EP-0617717-A1 PHOSPHORUS-CONTAINING TRIAZINE COMPOUNDS AND THEIR USE COURTAULDS PLC (GB) 1994-10-05 EP disclosed
WO-1993012173-A2 PHOSPHORUS-CONTAINING TRIAZINE COMPOUNDS AND THEIR USE COURTAULDS PLC (GB) 1993-06-24 WO disclosed