Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396458 | 0.82 | LMNA (0.52) | ALDH1A1TSHRALOX15LMNAPOLB | |
| Acetone SCHEMBL10636901 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TSHRALOX15LMNATDP1 | |
| Urea SCHEMBL28952838 | 0.76 | — | — | |
| Bicarbonate SCHEMBL15346242 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRALOX15LMNABLM | |
| SCHEMBL7611193 | 0.76 | LMNA (0.41) | ALDH1A1TSHRALOX15LMNATDP1 | |
| SCHEMBL20781 | 0.76 | — | — | |
| SCHEMBL1332087 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL10340047 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRALOX15LMNATDP1 | |
| SCHEMBL9137101 | 0.74 | POLB (0.52) | ALDH1A1TSHRALOX15LMNATDP1 | |
| Phosphonic Acid SCHEMBL7528825 | 0.71 | ALDH1A1 (0.57) | ALDH1A1TSHRALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423223-B1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | PEGBIO CO LTD (CN) | 2015-04-15 | — | — | EP | disclosed |
| US-8575097-B2 | Exendin variant and conjugate thereof | PEGBIO CO., LTD. (CN) | 2013-11-05 | — | — | US | disclosed |
| US-20120196795-A1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | PEGBIO CO., LTD. (CN) | 2012-08-02 | — | — | US | disclosed |
| EP-2423223-A1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | Pegbio Co., Ltd. (CN) | 2012-02-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196795-A1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | GLP1R, IAPP, GIPR | ALDH1A1 4434/4885TSHR 1596/4885ALOX15 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.