SCHEMBL7528955

SCHEMBL7528955

O=C(Nc1ccc(C=Cc2ccccc2)c(C(=O)O)c1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
PKM P14618 3/20 0.57
SNCA P37840 3/20 0.56
ITGB3 P05106 1/20 0.54
ITGAV P06756 1/20 0.54
ITGA2B P08514 1/20 0.54
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
MEN1 O00255 3/20 0.54
MAPT P10636 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.54
KCNK3 O14649 1/20 0.51
KCNK9 Q9NPC2 1/20 0.51
GRIK1 P39086 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HTT P42858 1/20 0.49
PTPN1 P18031 2/20 0.49
PABPC1 P11940 1/20 0.49
NR1H4 Q96RI1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7528948 1.00 KMT2A (0.57) KMT2APKMSNCAITGB3ITGAV
SCHEMBL7529037 0.84 SNCA (0.43) KMT2APKMSNCAITGB3ITGAV
SCHEMBL7529027 0.84 SNCA (0.43) KMT2APKMSNCAITGB3ITGAV
SCHEMBL7529029 0.84 SNCA (0.46) KMT2APKMSNCAITGB3ITGAV
SCHEMBL7528775 0.82 PTPN1 (0.46) KMT2APKMSNCAITGB3ITGAV
SCHEMBL7528779 0.82 PTPN1 (0.46) KMT2ASNCAITGB3ITGAVITGA2B
SCHEMBL7528772 0.82 PTPN1 (0.46) KMT2ASNCAITGB3ITGAVITGA2B
SCHEMBL7644901 0.81 RAB9A (0.58) KMT2APKMSNCANPC1RAB9A
SCHEMBL22543054 0.79 SNCA (0.83) KMT2APKMSNCANPC1RAB9A
SCHEMBL11593167 0.79 KMT2A (0.76) KMT2APKMNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032218-A1 Substituted stilbenes as glucose uptake enhancers TELIK, INC. 2002-03-14 US claimed
US-6479548-B2 P-(BENZOYLAMINO)STILBENE DERIVATIVES TELIK, INC. 2002-11-12 US disclosed
US-20020032218-A1 Substituted stilbenes as glucose uptake enhancers TELIK, INC. 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032218-A1 Substituted stilbenes as glucose uptake enhancers SLC2A1, SLC2A8, SLC2A2 KMT2A 3788/4885PKM 378/4885SNCA 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.