Resveratrol

Resveratrol

SCHEMBL7529004

C(=C/c1ccccc1)\c1ccccc1.Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.83
PTGS1 P23219 4/20 0.83
CYP1A1 P04798 4/20 0.83
CYP1A2 P05177 3/20 0.83
MEN1 O00255 3/20 0.83
ALDH1A1 P00352 3/20 0.83
TP53 P04637 3/20 0.83
CYP3A4 P08684 3/20 0.83
MAPT P10636 3/20 0.83
HPGD P15428 3/20 0.83
KMT2A Q03164 3/20 0.83
SMN1; SMN2 Q16637 3/20 0.83
HSD17B10 Q99714 3/20 0.83
LMNA P02545 3/20 0.83
CYP19A1 P11511 3/20 0.83
PTGS2 P35354 3/20 0.83
CYP1B1 Q16678 3/20 0.83
CA12 O43570 2/20 0.83
CA1 P00915 2/20 0.83
CA2 P00918 2/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resveratrol SCHEMBL27716066 1.00 KDM4E (0.83) KDM4EPTGS1CYP1A1CYP1A2MEN1
Resveratrol SCHEMBL721421 1.00 KDM4E (0.83) KDM4EPTGS1CYP1A1CYP1A2MEN1
Resveratrol SCHEMBL15441562 0.96 KDM4E (0.83) KDM4EPTGS1CYP1A1CYP1A2MEN1
Resveratrol SCHEMBL15441560 0.96 KDM4E (0.83) KDM4EPTGS1CYP1A1CYP1A2MEN1
Resveratrol SCHEMBL28307179 0.96 KDM4E (0.91) KDM4EPTGS1CYP1A1CYP1A2MEN1
Pinosylvin SCHEMBL9419839 0.93 LCK (0.71) KDM4EPTGS1CYP1A1CYP1A2MEN1
Pinosylvin SCHEMBL3940383 0.93 LCK (0.71) KDM4EPTGS1CYP1A1CYP1A2MEN1
Pinosylvin SCHEMBL7075363 0.93 LCK (0.71) KDM4EPTGS1CYP1A1CYP1A2MEN1
Pinosylvin SCHEMBL454262 0.93 LCK (0.71) KDM4EPTGS1CYP1A1CYP1A2MEN1
Pinosylvin SCHEMBL20455852 0.93 LCK (0.71) KDM4EPTGS1CYP1A1CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9925153-B2 Therapeutic agents for skin diseases and conditions STC.UNM (US) 2018-03-27 US disclosed
US-9597299-B2 Method for treating gefitinib-resistant non-small-cell lung cancer MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) 2017-03-21 US disclosed
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM 2016-10-06 US disclosed
US-20160158163-A1 Method For Treating Gefitinib-Resistant Non-Small-Cell Lung Cancer MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-06-09 US disclosed
WO-2015085143-A2 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM (US) 2015-06-11 WO disclosed
US-20020110604-A1 Composition exhibiting synergistic antioxidant activity ASHNI NATURACEUTICALS, INC. 2002-08-15 US disclosed
WO-2002013835-A1 COMPOSITION EXHIBITING SYNERGISTIC ANTIOXIDANT ACTIVITY ASHNI NATURACEUTICALS, INC. (US) 2002-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS CUTA, TSLP, ELANE KDM4E 3199/4885PTGS1 1081/4885CYP1A1 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.