Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263805 | 0.77 | CA1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL7461497 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL7964491 | 0.73 | KDM4E (0.60) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL9901098 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL15177531 | 0.72 | CA1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL10227610 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL13813804 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL9901826 | 0.71 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL8370932 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL25173859 | 0.69 | ACHE (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032572-B1 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 2002-12-11 | — | — | EP | disclosed |