Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.70 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.70 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.70 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.70 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.70 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.70 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527962 | 0.88 | GRIN2B (0.55) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8542333 | 0.86 | GRIN2B (0.73) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL6998090 | 0.85 | GRIN2B (0.57) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8114274 | 0.85 | GRIN2B (0.60) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL7585018 | 0.83 | GRIN2B (0.51) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL7228618 | 0.83 | GRIN2B (0.61) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL1908150 | 0.83 | GRIN2B (1.00) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8872091 | 0.82 | GRIN2B (0.67) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8548110 | 0.78 | GRIN2B (0.64) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL9053418 | 0.78 | CCR3 (0.65) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030422-A1 | USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030422-A1 | USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030422-A1 | USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |