Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506144 | 0.81 | ALDH1A1 (0.53) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL19691830 | 0.80 | RAB9A (0.77) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL15018695 | 0.78 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL6494694 | 0.78 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL925181 | 0.77 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL12781082 | 0.76 | TSHR (0.56) | RAB9AHPGDTSHRMAPK1L3MBTL1 | |
| SCHEMBL4901340 | 0.76 | HRH3 (0.47) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL7496666 | 0.76 | RAB9A (0.66) | RAB9AMAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7529835 | 0.75 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2HPGDTSHR | |
| SCHEMBL7075430 | 0.75 | MAPT (0.56) | RAB9AMAPTSMN1; SMN2HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190710-A1 | PREVENTIVE OR THERAPEUTIC DRUGS FOR DIABETES | SHIONOGI & CO., LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |