Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.79 |
| ▸ | DRD3 | P35462 | 7/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.79 |
| ▸ | DRD4 | P21917 | 3/20 | 0.72 |
| ▸ | HTR2A | P28223 | 8/20 | 0.64 |
| ▸ | HTR2C | P28335 | 8/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7526532 | 0.99 | DRD2 (0.78) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7531662 | 0.90 | DRD3 (0.67) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7531760 | 0.89 | DRD3 (0.63) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7526148 | 0.88 | DRD3 (0.62) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7534187 | 0.87 | DRD2 (0.93) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7526939 | 0.86 | DRD3 (0.77) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7769953 | 0.85 | DRD2 (0.75) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7769974 | 0.85 | DRD2 (0.76) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7057755 | 0.85 | DRD2 (0.74) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7528464 | 0.84 | DRD2 (0.79) | DRD2DRD3ADRA1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898567-B1 | N-AMINOALKYL-1-BIPHENYLENYL-2-CARBOXAMIDES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2002-04-03 | — | — | EP | claimed |