Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28266443 | 0.86 | CHRM2 (0.52) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| Methacrylic Acid SCHEMBL4069606 | 0.86 | RAB9A (0.45) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL11287710 | 0.83 | BLM (0.45) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL15435991 | 0.83 | CHRM2 (0.45) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL15091 | 0.83 | CA12 (0.52) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL4331422 | 0.83 | CA12 (0.52) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL24784667 | 0.81 | BLM (0.48) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL30622147 | 0.81 | BLM (0.48) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL31524126 | 0.81 | BLM (0.48) | RAB9AKDM4EALDH1A1CHRM2CHRM4 | |
| SCHEMBL29638790 | 0.81 | BLM (0.48) | RAB9AKDM4EALDH1A1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189607-A2 | ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES | Washington State University Research Foundation (US) | 2002-03-27 | — | — | EP | claimed |
| WO-2000059492-A2 | ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-10-12 | — | — | WO | claimed |
| EP-1189607-A2 | ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES | Washington State University Research Foundation (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000059492-A2 | ANTI-TUMOR ACTIVITY OF VITAMIN E, CHOLESTEROL, TAXOL AND BETULINIC ACID DERIVATIVES | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-10-12 | — | — | WO | disclosed |