Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7529345 | 0.86 | RAB9A (0.54) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| Acetone SCHEMBL28266443 | 0.84 | CHRM2 (0.52) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL27816657 | 0.83 | CHRM1 (0.50) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL11969913 | 0.82 | THRB (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL3644189 | 0.82 | RAB9A (0.42) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL319586 | 0.82 | THRB (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL771008 | 0.80 | THRB (0.61) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL389440 | 0.80 | THRB (0.61) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL28172340 | 0.80 | CHRM2 (0.47) | RAB9ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL19480170 | 0.79 | CHRM2 (0.41) | RAB9ACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306380-A1 | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | UBE INDUSTRIES, LTD. (JP) | 2009-12-10 | — | — | US | claimed |
| US-20090306380-A1 | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | UBE INDUSTRIES, LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090306380-A1 | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | UBE INDUSTRIES, LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090041843-A1 | PHARMACEUTICAL PREPARATION HAVING EXCELLENT PHOTOSTABILITY | KOWA CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-1944029-A1 | PHARMACEUTICAL PREPARATION HAVING EXCELLENT PHOTOSTABILITY | Kowa Company, Ltd. (JP) | 2008-07-16 | — | — | EP | disclosed |
| CN-101166713-A | Process for producing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | UBE INDUSTRIES (JP) | 2008-04-23 | — | — | CN | disclosed |
| WO-2006115237-A1 | PROCESS FOR PRODUCING 4-AMINO-2-ALKYLTHIO-5-PYRIMIDINECARBALDEHYDE | UBE INDUSTRIES, LTD. (JP) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306380-A1 | Process for preparing 4-amino-2-alkylthio-5-pyrimidinecarbaldehyde | NUDT1, DPYD, TPMT | RAB9A 4690/4885CHRM2 3934/4885CHRM4 3394/4885 |
| US-20090041843-A1 | PHARMACEUTICAL PREPARATION HAVING EXCELLENT PHOTOSTABILITY | HMGCR, PCSK9, CYP4A11 | RAB9A 439/4885CHRM2 3569/4885CHRM4 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.