SCHEMBL7529408

SCHEMBL7529408

CCCCC(O)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
PLA2G4B P0C869 3/20 0.47
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
RARB P10826 9/20 0.45
MEN1 O00255 1/20 0.43
RARA P10276 1/20 0.43
MTOR P42345 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840752 0.95 TP53 (0.50) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL5609102 0.94 TP53 (0.53) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL7529405 0.93 TSHR (0.46) TSHRMAPTALDH1A1MEN1KMT2A
SCHEMBL2061233 0.90 MAPT (0.49) TP53TSHRPLA2G4BMAPTALDH1A1
Terephthalic Acid SCHEMBL8439001 0.90 MAPT (0.49) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL25170017 0.89 LMNA (0.50) TP53TSHRALDH1A1MEN1KMT2A
SCHEMBL28350137 0.87 LMNA (0.49) TP53TSHRALDH1A1MEN1KMT2A
SCHEMBL8528683 0.87 ALDH1A1 (0.47) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL6505943 0.86 UTS2R (0.45) TSHRALDH1A1MEN1KMT2A
SCHEMBL7870404 0.84 ALDH1A1 (0.57) TP53TSHRPLA2G4BMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780340-B1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORP (US) 2002-03-20 EP claimed
EP-0747323-B1 Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same AMCOL INTERNATIONAL CORP (US) 2001-12-12 EP claimed
US-6242500-B1 Intercalates and exfoliates formed with long chain (C6+) or aromatic matrix polymer-compatible monomeric, oligomeric or polymeric intercalant compounds, and composite materials containing same AMCOL INTERNATIONAL CORPORATION 2001-06-05 US claimed
US-6057396-A INTERCALATE HAVING MOLAR RATIO OF MODIFIER TO INTERLAYER CATION OF ONE TO FIVE TO ACHIEVE SORPTION AND COMPLEXING BETWEEN ADJACENT LAYERS OF MATERIAL TO EXPAND SPACING AMCOL INTERNATIONAL CORPORATION (US) 2000-05-02 US claimed
US-5952095-A AN INTERCALATED PHYLLOSILICATE COMPLEX CAN BE COMBINED WITH AN ORGANIC LIQUID INTO A VISCOUS CARRIER MATERIAL, FOR DELIVERY AN ACTIVE MATERIAL, OR AS PLASTICIZERS FOR AN POLYMER TO FORM A STRONG, FILLED POLYMER MATRIX AMCOL INTERNATIONAL CORPORATION (US) 1999-09-14 US claimed
US-5880197-A MULTILAYER NATERIAL WITH PHYLLOSILICATES AND MONOMER AMINES OR AMIDES WITH PLATES AMCOL INTERNATIONAL CORPORATION (US) 1999-03-09 US claimed
US-5804613-A Intercalates and exfoliates formed with monomeric carbonyl-functional organic compounds, including carboxylic and polycarboxylic acids; aldehydes; and ketones; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORPORATION (US) 1998-09-08 US claimed
EP-0846661-A2 Intercalates formed by co-intercalation of monomer, oligomer or polymer intercalants and surface modifier intercalants and layered materials and nanocomposites prepared with the intercalates AMCOL INTERNATIONAL CORPORATION (US) 1998-06-10 EP claimed
EP-0846660-A2 Intercalates and exfoliates formed with long chain monomeric organic intercalant compounds having at least ten carbon atoms and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1998-06-10 EP claimed
EP-0780340-A1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORPORATION (US) 1997-06-25 EP claimed
EP-0747323-A1 Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1996-12-11 EP claimed
US-5578672-A MIXING PHYLLOSILICATE WITH A POLYMER AND LIQUID CARRIER, EXTRUSION THROUGH DIE; COMPOSITES, AUTOMOBILE PARTS AMCOL INTERNATIONAL CORPORATION (US) 1996-11-26 US claimed
US-5552469-A SILICATE AMCOL INTERNATIONAL CORPORATION (US) 1996-09-03 US claimed