SCHEMBL7529418

SCHEMBL7529418

CCCC(O)COC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.62
ADRB2 P07550 14/20 0.50
ADRB1 P08588 14/20 0.50
ADRB3 P13945 14/20 0.50
ALDH1A1 P00352 3/20 0.49
PLA2G4B P0C869 1/20 0.47
LMNA P02545 2/20 0.45
CYP3A4 P08684 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926231 0.93 ADRB2 (0.54) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL31307131 0.91 MAPT (0.59) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL4955980 0.89 ALDH1A1 (0.64) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL27754247 0.87 ADRB2 (0.64) ADRB2ADRB1ADRB3ALDH1A1LMNA
SCHEMBL27256400 0.87 MAPT (0.71) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL1648610 0.85 MAPT (0.55) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL27103108 0.84 MAPT (0.77) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL23926216 0.83 ALDH1A1 (0.57) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL18087444 0.82 MAPT (0.59) MAPTADRB2ADRB1ADRB3ALDH1A1
SCHEMBL28152656 0.82 MAPT (0.60) MAPTADRB2ADRB1ADRB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780340-B1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORP (US) 2002-03-20 EP claimed
EP-0747323-B1 Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same AMCOL INTERNATIONAL CORP (US) 2001-12-12 EP claimed
US-6242500-B1 Intercalates and exfoliates formed with long chain (C6+) or aromatic matrix polymer-compatible monomeric, oligomeric or polymeric intercalant compounds, and composite materials containing same AMCOL INTERNATIONAL CORPORATION 2001-06-05 US claimed
US-6057396-A INTERCALATE HAVING MOLAR RATIO OF MODIFIER TO INTERLAYER CATION OF ONE TO FIVE TO ACHIEVE SORPTION AND COMPLEXING BETWEEN ADJACENT LAYERS OF MATERIAL TO EXPAND SPACING AMCOL INTERNATIONAL CORPORATION (US) 2000-05-02 US claimed
US-5952095-A AN INTERCALATED PHYLLOSILICATE COMPLEX CAN BE COMBINED WITH AN ORGANIC LIQUID INTO A VISCOUS CARRIER MATERIAL, FOR DELIVERY AN ACTIVE MATERIAL, OR AS PLASTICIZERS FOR AN POLYMER TO FORM A STRONG, FILLED POLYMER MATRIX AMCOL INTERNATIONAL CORPORATION (US) 1999-09-14 US claimed
US-5880197-A MULTILAYER NATERIAL WITH PHYLLOSILICATES AND MONOMER AMINES OR AMIDES WITH PLATES AMCOL INTERNATIONAL CORPORATION (US) 1999-03-09 US claimed
US-5804613-A Intercalates and exfoliates formed with monomeric carbonyl-functional organic compounds, including carboxylic and polycarboxylic acids; aldehydes; and ketones; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORPORATION (US) 1998-09-08 US claimed
EP-0846660-A2 Intercalates and exfoliates formed with long chain monomeric organic intercalant compounds having at least ten carbon atoms and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1998-06-10 EP claimed
EP-0846661-A2 Intercalates formed by co-intercalation of monomer, oligomer or polymer intercalants and surface modifier intercalants and layered materials and nanocomposites prepared with the intercalates AMCOL INTERNATIONAL CORPORATION (US) 1998-06-10 EP claimed
EP-0780340-A1 Intercalates and exfoliates formed with functional monomeric organic compounds; composite materials containing same and methods of modifying rheology therewith AMCOL INTERNATIONAL CORPORATION (US) 1997-06-25 EP claimed
EP-0747323-A1 Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1996-12-11 EP claimed
US-5578672-A MIXING PHYLLOSILICATE WITH A POLYMER AND LIQUID CARRIER, EXTRUSION THROUGH DIE; COMPOSITES, AUTOMOBILE PARTS AMCOL INTERNATIONAL CORPORATION (US) 1996-11-26 US claimed
US-5552469-A SILICATE AMCOL INTERNATIONAL CORPORATION (US) 1996-09-03 US claimed