Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529421 | 1.00 | ADORA3 (0.57) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL7527246 | 0.90 | ADORA3 (0.66) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL7527254 | 0.90 | ADORA3 (0.66) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL7525284 | 0.88 | ADORA3 (0.60) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL7525293 | 0.88 | ADORA3 (0.60) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL8375864 | 0.87 | ADORA3 (0.58) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL7526418 | 0.87 | ADORA3 (0.59) | ADORA3ADORA1NT5E | |
| SCHEMBL7526426 | 0.87 | ADORA3 (0.59) | ADORA3ADORA1NT5E | |
| SCHEMBL7531052 | 0.85 | ADORA3 (0.61) | ADORA3ADORA1NT5EADORA2A | |
| SCHEMBL7531045 | 0.85 | ADORA3 (0.61) | ADORA3ADORA1NT5EADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901499-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-04-10 | — | — | EP | claimed |
| US-5998388-A | N6-PHENYL-SUBSTITUTED | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0901499-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-04-10 | — | — | EP | disclosed |
| US-5998388-A | N6-PHENYL-SUBSTITUTED | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |