SCHEMBL7529443

SCHEMBL7529443

Cc1ncnc(NN)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 3/20 0.36
XDH P47989 1/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PDPK1 O15530 1/20 0.33
EGFR P00533 2/20 0.33
GALR3 O60755 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MKNK1 Q9BUB5 1/20 0.31
GOT1 P17174 1/20 0.31
METAP2 P50579 1/20 0.30
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22048110 0.77 MEN1 (0.38) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL3581232 0.75
SCHEMBL27949052 0.74 MEN1 (0.40) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL3706204 0.71
SCHEMBL3036614 0.70
SCHEMBL15834728 0.69 CHRM4 (0.40) LMNASMN1; SMN2EGFR
SCHEMBL4978982 0.68 XDH (0.38) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL21598402 0.68 NOS2 (0.39) NPC1RAB9AKDM4EMAPTSMN1; SMN2
SCHEMBL11110616 0.67 EGFR (0.54) MEN1KMT2ARAB9ALMNAHTT
SCHEMBL12832960 0.67 MAPT (0.46) MEN1KMT2ANPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020015915-A1 Azo compound containing metal and optical recording medium using the compound YAMADA CHEMICAL CO., LTD. (JP) 2002-02-07 US disclosed