Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 8/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 8/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529625 | 0.74 | CARM1 (0.56) | CARM1PRMT6SLC6A5 | |
| SCHEMBL7530604 | 0.74 | CARM1 (0.61) | CARM1PRMT6DRD1SLC6A5 | |
| SCHEMBL3441472 | 0.73 | CARM1 (0.52) | CARM1PRMT6SIGMAR1DRD1DRD4 | |
| SCHEMBL12049739 | 0.73 | CARM1 (0.70) | CARM1PRMT6SIGMAR1DRD4NAAA | |
| SCHEMBL12041767 | 0.72 | CARM1 (0.65) | CARM1PRMT6SIGMAR1BCHESLC6A5 | |
| SCHEMBL3441473 | 0.72 | CARM1 (0.47) | CARM1PRMT6SIGMAR1DRD1DRD4 | |
| SCHEMBL19090879 | 0.71 | CARM1 (0.86) | CARM1PRMT6SIGMAR1SLC6A5 | |
| SCHEMBL381729 | 0.71 | CARM1 (0.64) | CARM1PRMT6SIGMAR1BCHESLC6A5 | |
| SCHEMBL19080588 | 0.71 | CARM1 (0.70) | CARM1PRMT6SIGMAR1BCHESLC6A5 | |
| Lithium Ion SCHEMBL381730 | 0.70 | CARM1 (0.63) | CARM1PRMT6NAAABCHESLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190710-A1 | PREVENTIVE OR THERAPEUTIC DRUGS FOR DIABETES | SHIONOGI & CO., LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |