Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.59 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529625 | 0.86 | CARM1 (0.56) | CARM1PRMT6CACNA1BCACNA1HSLC6A5 | |
| SCHEMBL19090879 | 0.79 | CARM1 (0.86) | CARM1PRMT6SLC6A5HRH3 | |
| SCHEMBL20988126 | 0.77 | CARM1 (0.71) | CARM1PRMT6SLC6A5HRH3 | |
| SCHEMBL19080588 | 0.76 | CARM1 (0.70) | CARM1PRMT6SLC6A5HRH3 | |
| SCHEMBL4083888 | 0.76 | HRH3 (0.63) | HRH3 | |
| SCHEMBL12049739 | 0.76 | CARM1 (0.70) | CARM1PRMT6SLC6A5DRD3 | |
| SCHEMBL12041767 | 0.75 | CARM1 (0.65) | CARM1PRMT6SLC6A5HRH3 | |
| SCHEMBL5814284 | 0.75 | CARM1 (0.50) | CARM1PRMT6SLC6A5DRD2DRD3 | |
| SCHEMBL381729 | 0.74 | CARM1 (0.64) | CARM1PRMT6SLC6A5HRH3 | |
| SCHEMBL7529636 | 0.74 | CARM1 (0.57) | CARM1PRMT6SLC6A5DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190710-A1 | PREVENTIVE OR THERAPEUTIC DRUGS FOR DIABETES | SHIONOGI & CO., LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |