Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529671 | 1.00 | CHRNB4 (0.47) | CHRNB4CHRNA3PSMB5ACMSDHTR1A | |
| SCHEMBL19910204 | 0.98 | CHRNB4 (0.49) | CHRNB4CHRNA3PSMB5ACMSDHTR1A | |
| SCHEMBL20567911 | 0.93 | CHRNB4 (0.46) | CHRNB4CHRNA3PSMB5ACMSDHTR1A | |
| SCHEMBL28039620 | 0.83 | ACHE (0.46) | CHRNB4CHRNA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26493779 | 0.82 | RAB9A (0.45) | CHRNB4CHRNA3PSMB5ACMSDMAPK14 | |
| SCHEMBL8836181 | 0.79 | CHRNB4 (0.55) | CHRNB4CHRNA3NPC1MAPTRAB9A | |
| SCHEMBL11670468 | 0.79 | PSMB5 (0.46) | PSMB5ACMSDPTGS2HDAC1HDAC2 | |
| SCHEMBL16718964 | 0.79 | PSMB5 (0.46) | PSMB5ACMSDPTGS2HDAC1HDAC2 | |
| SCHEMBL11307172 | 0.79 | PSMB5 (0.46) | PSMB5ACMSDPTGS2HDAC1HDAC2 | |
| SCHEMBL15823144 | 0.79 | CHRNB4 (0.47) | CHRNB4CHRNA3PSMB5ACMSDHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205246-C | Process for preparation of addition products of difunctional telechelic polyolefins from cyclic olefins by olefin metathesis reaction | CALIFORNIA TECHNOLOGY UNIV (US) | 2005-06-08 | — | — | CN | claimed |
| EP-0626402-B1 | Linear telechelic difunctional polymers and process for their preparation. | CALIFORNIA INST OF TECHN (US) | 2002-07-31 | — | — | EP | claimed |
| EP-0857183-B1 | PROCESS FOR PREPARATION OF ADDITION PRODUCTS OF DIFUNCTIONAL TELECHELIC POLYOLEFINS FROM CYCLIC OLEFINS BY OLEFIN METATHESIS REACTION | CALIFORNIA INST OF TECHN (US) | 2001-11-07 | — | — | EP | claimed |
| US-6143851-A | Process for preparation of addition products of difunctional telechelic polyolefins from cyclic olefins by olefin metathesis reaction | BP AMOCO CORPORATION (US) | 2000-11-07 | — | — | US | claimed |
| CN-1198754-A | Process for preparation of addition products of difunctional telechelic polyolefins from cyclic olefins by olefin metathesis reaction | AMOCO CORP (US) | 1998-11-11 | — | — | CN | claimed |
| EP-0857183-A1 | PROCESS FOR PREPARATION OF ADDITION PRODUCTS OF DIFUNCTIONAL TELECHELIC POLYOLEFINS FROM CYCLIC OLEFINS BY OLEFIN METATHESIS REACTION | AMOCO CORPORATION (US) | 1998-08-12 | — | — | EP | claimed |
| US-5731383-A | USED FOR HIGH DENSITY POLYESTERS, POLYAMIDES, POLYUREAS, POLYURETHANES | AMOCO CORPORATION (US) | 1998-03-24 | — | — | US | claimed |
| WO-1998006771-A1 | PROCESS FOR PREPARATION OF ADDITION PRODUCTS OF DIFUNCTIONAL TELECHELIC POLYOLEFINS FROM CYCLIC OLEFINS BY OLEFIN METATHESIS REACTION | AMOCO CORPORATION (US) | 1998-02-19 | — | — | WO | claimed |
| US-5621047-A | CATALYTIC CROSS-METATHESIS REACTION OF OLEFINS WITH ALKYL (METH)ACRYLATES YIELDS PURE, UNSATURATED POLYMERS HAVING REACTIVE END GROUPS | AMOCO CORPORATION (US) | 1997-04-15 | — | — | US | claimed |
| US-5589548-A | Process for preparing difunctional telechelic linear non-crosslinked polyolefins | AMOCO CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| US-5512635-A | OLEFIN METATHESIS PROCESS; CROSSLINKING INHIBITION | AMOCO CORPORATION (US) | 1996-04-30 | — | — | US | claimed |
| EP-0626402-A2 | Process for preparing linear monofunctional and telechelic difunctional polymers and compositions obtained thereby | AMOCO CORPORATION (US) | 1994-11-30 | — | — | EP | claimed |
| CN-1205246-C | Process for preparation of addition products of difunctional telechelic polyolefins from cyclic olefins by olefin metathesis reaction | CALIFORNIA TECHNOLOGY UNIV (US) | 2005-06-08 | — | — | CN | disclosed |
| US-20020111447-A1 | Novel end-functionalized polyolefin prepared via ring opening metathesis polymerization in the presence of a novel chain transfer agent, and a process for the preparation of the end-functionalized polyolefin via ring opening metathesis polymerization | BAYER CORPORATION | 2002-08-15 | — | — | US | disclosed |
| EP-0626402-B1 | Linear telechelic difunctional polymers and process for their preparation. | CALIFORNIA INST OF TECHN (US) | 2002-07-31 | — | — | EP | disclosed |
| US-20020077428-A1 | PROCESS FOR THE SYNTHESIS OF HYDROXYL-END GROUP FUNCTIONALIZED POLYBUTADIENES | BAYER CORPORATION | 2002-06-20 | — | — | US | disclosed |
| US-5589548-A | Process for preparing difunctional telechelic linear non-crosslinked polyolefins | AMOCO CORPORATION (US) | 1996-12-31 | — | — | US | disclosed |
| US-5559190-A | Difunctional telechelic linear non-crosslinked polyolefins | AMOCO CORPORATION (US) | 1996-09-24 | — | — | US | disclosed |
| US-5512635-A | OLEFIN METATHESIS PROCESS; CROSSLINKING INHIBITION | AMOCO CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0626402-A2 | Process for preparing linear monofunctional and telechelic difunctional polymers and compositions obtained thereby | AMOCO CORPORATION (US) | 1994-11-30 | — | — | EP | disclosed |