Fluoride Ion

Fluoride Ion

SCHEMBL7529778

[F-].[F-].c1ccc([Bi+2](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
APP P05067 1/20 0.39
MIF P14174 1/20 0.36
TSHR P16473 5/20 0.35
TDP1 Q9NUW8 4/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
ALOX12 P18054 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.33
CA7 P43166 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3127798 0.92 APP (0.39) ALDH1A1APPTSHRTDP1CA1
Water SCHEMBL3133133 0.92 APP (0.39) ALDH1A1APPMIFTSHRTDP1
Bromide SCHEMBL11573800 0.92 APP (0.39) ALDH1A1APPMIFTSHRTDP1
Iodide SCHEMBL11576793 0.92 APP (0.39) ALDH1A1APPMIFTSHRTDP1
SCHEMBL3127824 0.78 ALDH1A1 (0.48) ALDH1A1TSHRTDP1ALOX12LMNA
Acetic Acid SCHEMBL17892007 0.74 HSD17B10 (0.44) ALDH1A1TSHRTDP1CA1CA2
Trichloroacetic Acid SCHEMBL23088971 0.69 CYP1A2 (0.40) ALDH1A1TSHRCA2GLACA4
Fluoride Ion SCHEMBL912529 0.65 ACHE (0.53) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL644381 0.58
Biphenyl SCHEMBL28831377 0.58 ALDH1A1 (0.82) ALDH1A1TDP1CA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112794786-A Method for producing polyfluorobenzene derivative from tetrachloroethylene byproduct 衢州乾达科技有限公司 2021-05-14 CN claimed
US-20210399237-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-23 US disclosed
EP-0805815-B1 Use of bismuth compounds for the manufacture of medicaments for the treatment of gastric disorders caused by Helicobacter pylori NYCOMED IMAGING AS (NO) 2002-04-10 EP disclosed
US-6303101-B1 TREATING A GASTROINTESTINAL DISORDER, ESPECIALLY AN ULCER CAUSED BY HELIOBACTER PYLORI. NYCOMED IMAGING AS (NO) 2001-10-16 US disclosed
US-6117412-A ADMINISTERING BISMUTH COMPOUND CONTAINING ADDITIONAL HEAVY ATOM AS CONTRAST ENHANCER; X-RAYS, MAGNETIC RESONANCE, ULTRASOUND, AND SCINTIGRAPHIC IMAGING NYCOMED IMAGING AS (NO) 2000-09-12 US disclosed
EP-0805815-A1 BISMUTH COMPOUNDS NYCOMED IMAGING A/S (NO) 1997-11-12 EP disclosed
WO-1996022994-A1 BISMUTH COMPOUNDS NYCOMED IMAGING A/S (NO) 1996-08-01 WO disclosed
US-4479960-A 2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO(2,1-B) THIAZOLE IN A DILUENT BAYER AG (DE) 1984-10-30 US disclosed
US-4414222-A TETRAMISOLE OR LEVAMISOLE WITH AN ALCOHOL OR ESTER BAYER AG (US) 1983-11-08 US disclosed
US-4336262-A Pour-on veterinary anthelmintic FISONS LTD. (GB) 1982-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210399237-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ALDH1A1 139/4885APP 2306/4885MIF 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.