Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535383 | 0.90 | MTNR1B (0.42) | POLBMTNR1BMTNR1AHMGCRHSD17B10 | |
| SCHEMBL7533057 | 0.88 | KMT2A (0.50) | MTNR1BMTNR1A | |
| SCHEMBL7529182 | 0.86 | POLB (0.51) | POLBMTNR1BMTNR1AHSD17B10 | |
| SCHEMBL7532128 | 0.84 | MTNR1B (0.40) | POLBMTNR1BMTNR1ARAB9A | |
| SCHEMBL7530000 | 0.83 | TNFSF11 (0.41) | HMGCR | |
| SCHEMBL7537430 | 0.83 | TNFSF11 (0.41) | HMGCR | |
| SCHEMBL7530056 | 0.83 | TNFSF11 (0.41) | HMGCR | |
| SCHEMBL5882460 | 0.82 | PDE4D (0.52) | HMGCR | |
| SCHEMBL7535390 | 0.80 | POLB (0.39) | POLBMTNR1BMTNR1AHSD17B10 | |
| SCHEMBL7530956 | 0.80 | HMGCR (0.40) | POLBHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |