Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530218 | 0.87 | HMGCR (0.41) | PDE4DMEN1TSHRKMT2A | |
| SCHEMBL7536283 | 0.86 | HMGCR (0.36) | MTNR1BMTNR1APDE4D | |
| SCHEMBL7529980 | 0.84 | POLB (0.43) | MTNR1BMTNR1APOLBRAB9A | |
| SCHEMBL8959275 | 0.83 | HMGCR (0.41) | POLBPDE4D | |
| SCHEMBL7535383 | 0.83 | MTNR1B (0.42) | MTNR1BMTNR1APOLBMEN1RAB9A | |
| SCHEMBL7533057 | 0.81 | KMT2A (0.50) | MTNR1BMTNR1AMEN1LMNAKMT2A | |
| SCHEMBL7529985 | 0.81 | TNFSF11 (0.39) | MTNR1BMTNR1APDE4DTSHR | |
| SCHEMBL7531040 | 0.81 | HMGCR (0.38) | MTNR1BMTNR1APOLBPDE4DMEN1 | |
| SCHEMBL7532058 | 0.80 | ELANE (0.37) | POLBLMNAKMT2A | |
| SCHEMBL7530400 | 0.80 | MTNR1A (0.36) | MTNR1BMTNR1APDE4DMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |