SCHEMBL7530192

SCHEMBL7530192

c1ccc2c(c1)-c1cccc(-c3cccc4oc5ccccc5c34)c1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
HPGD P15428 4/20 0.43
MAOA P21397 3/20 0.43
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
CASP1 P29466 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GLA P06280 2/20 0.43
CYP3A4 P08684 1/20 0.43
PGAM1 P18669 1/20 0.43
CASP7 P55210 1/20 0.43
NTRK1 P04629 1/20 0.43
PLK3 Q9H4B4 1/20 0.43
CDC14B O60729 1/20 0.40
CDC14A Q9UNH5 1/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30021661 1.00 ALDH1A1 (0.43) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL16670035 0.92 ALDH1A1 (0.50) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL3081231 0.89 ALDH1A1 (0.52) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL30550556 0.89 ALDH1A1 (0.52) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL30332810 0.89 CDC14B (0.40) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL16491784 0.88 NTRK1 (0.53) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL17229081 0.86 ALDH1A1 (0.45) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL30022467 0.86 ALDH1A1 (0.45) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL17431133 0.84 MAOA (0.43) ALDH1A1HPGDMAOAHSD17B10KDM4E
SCHEMBL17431144 0.84 MAOA (0.43) ALDH1A1HPGDMAOAHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868466-B1 SOIL RELEASE POLYMERS WITH FLUORESCENT WHITENING PROPERTIES PROCTER & GAMBLE (US) 2002-04-03 EP claimed
EP-0475907-A2 Process for the production of good quality moulded articles CIBA-GEIGY AG (CH) 1992-03-18 EP claimed