SCHEMBL7530233

SCHEMBL7530233

[CH2]Cc1ccc(CCCCCCCCC)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.63
ADRA2A P08913 2/20 0.63
ADORA3 P0DMS8 2/20 0.63
TACR2 P21452 2/20 0.63
SLC6A2 P23975 2/20 0.63
SLC6A4 P31645 2/20 0.63
SLC6A3 Q01959 2/20 0.63
ALDH1A1 P00352 2/20 0.63
HSD17B10 Q99714 2/20 0.63
KDM4E B2RXH2 1/20 0.63
LMNA P02545 1/20 0.63
SHBG P04278 1/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
HSPD1 P10809 1/20 0.63
ADRB3 P13945 1/20 0.63
HTR2C P28335 1/20 0.63
HSPE1 P61604 1/20 0.63
HIF1A Q16665 1/20 0.63
TST Q16762 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677469 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL2915276 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9753538 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1611473 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL698308 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1609476 0.98 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL363054 0.91 CA2 (0.54) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL23849704 0.88 ESR1 (0.77) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL2511615 0.88 ESR1 (0.77) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL10980557 0.88 ESR1 (0.77) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115210239-A Aromatic compound, organic semiconductor layer and organic thin film transistor 东曹株式会社 2022-10-18 CN disclosed
EP-1008429-B1 Paintable organopolysiloxane mold release compositions WACKER CHEMIE GMBH (DE) 2002-04-03 EP disclosed
US-6294007-B1 STABILITY WACKER SILICONES CORPORATION 2001-09-25 US disclosed
US-6194482-B1 CASTING RESIN OF EPOXY RESIN, ISOCYANURATE SILOXANE, FILLERS, PHOTO INITIATORS AND THERMAL INITIATORS SIEMENS AKTIENGESELLSCHAFT (DE) 2001-02-27 US disclosed
EP-1008429-A1 Paintable organopolysiloxane mold release compositions and processes for their use Wacker-Chemie GmbH (DE) 2000-06-14 EP disclosed
US-6037043-A UV-hardenable and thermally hardenable epoxy resins for underfilling electrical and electronic components SIEMENS AKTIENGESELLSCAFT (DE) 2000-03-14 US disclosed
EP-0523468-B1 Silicone imides SIEMENS AG (DE) 1996-10-09 EP disclosed
EP-0399199-B1 Silicone compounds containing isocyanurat groups SIEMENS AG (DE) 1994-07-27 EP disclosed
US-5302684-A Siliconimides SIEMENS AKTIENGESELLSCHAFT (DE) 1994-04-12 US disclosed
US-5239073-A Preparation of isocyanurate-containing organosilicon compounds SIEMENS AKTIENGESELLSCHAFT (DE) 1993-08-24 US disclosed
EP-0523468-A1 Silicone imides SIEMENS AKTIENGESELLSCHAFT (DE) 1993-01-20 EP disclosed
EP-0284863-B1 (METH)ACRYLIC-ACID-ESTER-MODIFIED ORGANIC POLYSILOXANES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ABHESIVE COATINGS Th. Goldschmidt AG (DE) 1992-12-02 EP disclosed
US-5101029-A ISOCYANURATE-CONTAINING ORGANOSILICON COMPOUNDS SIEMENS AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
EP-0283896-B1 OPTICAL FIBRE WITH A PRIMARY COATING OF ORGANOPOLYSILOXANES CONTAINING ACRYLIC-ESTER GROUPS SIEMENS AKTIENGESELLSCHAFT (DE) 1992-02-19 EP disclosed
EP-0399199-A2 Silicone compounds containing isocyanurat groups SIEMENS AKTIENGESELLSCHAFT (DE) 1990-11-28 EP disclosed
US-4969711-A Optical glass fiber with a primary coating of acrylic acid ester groups-containing organo-polysiloxanes SIEMENS AKTIENGESELLSCHAFT (DE) 1990-11-13 US disclosed
EP-0254799-B1 (METH)ACRYLIC ESTER MODIFIED ORGANOPOLYSILOXANES, PROCESS FOR MAKING THEM AND THEIR USE AS ADHESIVE COATING COMPOSITIONS Th. Goldschmidt AG (DE) 1990-06-13 EP disclosed
EP-0284863-A2 (Meth)acrylic-acid-ester-modified organic polysiloxanes, process for their preparation and their use as abhesive coatings Th. Goldschmidt AG (DE) 1988-10-05 EP disclosed
EP-0283896-A1 Optical fibre with a primary coating of organopolysiloxanes containing acrylic-ester groups SIEMENS AKTIENGESELLSCHAFT (DE) 1988-09-28 EP disclosed
EP-0254799-A1 (Meth)acrylic ester modified organopolysiloxanes, process for making them and their use as adhesive coating compositions Th. Goldschmidt AG (DE) 1988-02-03 EP disclosed