Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.52 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14190802 | 0.86 | KDM4E (0.76) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7108356 | 0.85 | KDM4E (0.74) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7108298 | 0.84 | KDM4E (0.72) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5800630 | 0.82 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL4197501 | 0.82 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5471150 | 0.81 | MEN1 (0.75) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL14479131 | 0.81 | KDM4E (0.73) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7108302 | 0.81 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5217325 | 0.81 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL6559744 | 0.81 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020437-A2 | BASIC COMPOUNDS CONTAINING TERTIARY AMIDES WITH ACTIVITY ON TACHYKININ RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2002-03-14 | — | — | WO | disclosed |