Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108356 | 0.98 | KDM4E (0.74) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7108302 | 0.86 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL14190802 | 0.85 | KDM4E (0.76) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7530265 | 0.84 | KDM4E (0.74) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7107818 | 0.83 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL4197501 | 0.81 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5800630 | 0.81 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL25356954 | 0.80 | KDM4E (0.51) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL26008244 | 0.80 | KDM4E (0.51) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL26009757 | 0.80 | KDM4E (0.51) | KDM4EHRH3MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030170173-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2003-09-11 | — | — | US | disclosed |
| EP-1283728-A2 | CONTRAST AGENTS | Amersham Health AS (NO) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001089584-A2 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030170173-A1 | Contrast agents | GBA1, RNASE1, MAN2B1 | KDM4E 4578/4885HRH3 2413/4885MEN1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.