Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butyltriphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyltriphenylphosphonium SCHEMBL9720844 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Butyltriphenylphosphonium SCHEMBL328957 | 0.95 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Butyltriphenylphosphonium SCHEMBL8437734 | 0.95 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Acetic Acid SCHEMBL3786910 | 0.93 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Acetic Acid SCHEMBL7871075 | 0.93 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Acetic Acid SCHEMBL10949251 | 0.93 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Butyltriphenylphosphonium SCHEMBL21296057 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Acetic Acid SCHEMBL9603313 | 0.89 | TSHR (0.55) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Acetic Acid SCHEMBL7877215 | 0.89 | TSHR (0.55) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| Butyltriphenylphosphonium SCHEMBL7871063 | 0.88 | CA2 (0.50) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |
| US-4584408-A | Preparation of 1,3-bis(aryloxy)-2-propanols | THE DOW CHEMICAL COMPANY (US) | 1986-04-22 | — | — | US | claimed |
| US-20240417532-A1 | CONDUCTIVE RESIN COMPOSITION | SAKATA INX CORPORATION (JP) | 2024-12-19 | — | — | US | disclosed |
| EP-4424769-A1 | CONDUCTIVE RESIN COMPOSITION | Sakata INX Corporation (JP) | 2024-09-04 | — | — | EP | disclosed |
| CN-118119662-A | Conductive resin composition | 阪田油墨股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023074680-A1 | CONDUCTIVE RESIN COMPOSITION | サカタインクス株式会社 | 2023-05-04 | — | — | WO | disclosed |
| US-11572467-B2 | Resin composition for acoustic matching layer, cured product, acoustic matching sheet, acoustic probe, acoustic measuring apparatus, method for producing acoustic probe, and acoustic matching layer material set | FUJIFILM CORPORATION (JP) | 2023-02-07 | — | — | US | disclosed |
| EP-3706438-A1 | RESIN COMPOSITION FOR ACOUSTIC MATCHING LAYER, CURED PRODUCT, ACOUSTIC MATCHING SHEET, ACOUSTIC WAVE PROBE, ACOUSTIC WAVE MEASUREMENT DEVICE, PRODUCTION METHOD FOR ACOUSTIC WAVE PROBE, AND MATERIAL SET FOR ACOUSTIC MATCHING LAYER | FUJIFILM Corporation (JP) | 2020-09-09 | — | — | EP | disclosed |
| US-20200255653-A1 | RESIN COMPOSITION FOR ACOUSTIC MATCHING LAYER, CURED PRODUCT, ACOUSTIC MATCHING SHEET, ACOUSTIC PROBE, ACOUSTIC MEASURING APPARATUS, METHOD FOR PRODUCING ACOUSTIC PROBE, AND ACOUSTIC MATCHING LAYER MATERIAL SET | FUJIFILM CORPORATION (JP) | 2020-08-13 | — | — | US | disclosed |
| EP-0944679-B1 | COATING AGENT- THE MANUFACTURE AND USE THEREOF | DU PONT (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-0944682-B1 | BONDING AGENT COMPOSITION, COATING AGENTS CONTAINING THEM, THEIR PRODUCTION AND USE | DU PONT (US) | 2002-03-27 | — | — | EP | disclosed |
| US-5710208-A | LACQUERS IN AUTOMOBILES | HERBERTS GMBH (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5686532-A | MULTILAYER LACQUER COATINGS USED IN AUTOMOBILES | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-11-11 | — | — | US | disclosed |
| EP-0797643-A1 | BINDER COMPOSITION, A COATING AGENT CONTAINING SAID BINDER COMPOSITION, ITS PRODUCTION AND USE | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1997-10-01 | — | — | EP | disclosed |
| EP-0597394-B1 | Binder composition, coating containing the same, manufacture and use thereof | HERBERTS & CO GMBH (DE) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995030719-A1 | BINDER COMPOSITION, A COATING AGENT CONTAINING SAID BINDER COMPOSITION, ITS PRODUCTION AND USE | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1995-11-16 | — | — | WO | disclosed |
| US-5414053-A | Improved shelf life, bonding metals, fiberglass | ESSEX SPECIALTY PRODUCTS, INC. (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0598280-A2 | Binder composition, coating containing it, its preparation and its use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0597394-A2 | Binder composition, coating containing the same, manufacture and use thereof | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-4584408-A | Preparation of 1,3-bis(aryloxy)-2-propanols | THE DOW CHEMICAL COMPANY (US) | 1986-04-22 | — | — | US | disclosed |