Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096896 | 0.88 | CA1 (0.40) | CA1CA2TSHR | |
| SCHEMBL5997017 | 0.88 | CA1 (0.40) | CA1CA2TSHR | |
| SCHEMBL12910675 | 0.83 | PPARA (0.35) | CA1PPARACA2CA7CA9 | |
| SCHEMBL10094922 | 0.83 | PPARA (0.35) | CA1PPARACA2CA7CA9 | |
| SCHEMBL5997770 | 0.81 | KMT2A (0.33) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL5997778 | 0.81 | KMT2A (0.33) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL14226486 | 0.80 | PPARA (0.39) | CA1PPARACA2CA7CA9 | |
| SCHEMBL9304310 | 0.80 | MAPT (0.41) | KMT2ATSHRMAPTCTSBELANE | |
| SCHEMBL9304303 | 0.80 | MAPT (0.41) | KMT2ATSHRMAPTCTSBELANE | |
| SCHEMBL6807099 | 0.80 | CTSK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052028-A1 | Bio-intermediates for use in the chemical synthesis of polyketides | KOSAN BIOSCIENCES, INC. | 2002-05-02 | — | — | US | disclosed |